Evaluation of the gonadotropic ratios among men with varying sperm quality

This study was designed to determine the levels of serum LH and FSH, along with their ratios, among men with varying sperm quality. One hundred fifty married men, presenting with a complaint of infertility, which had been evaluated for their seminal profile, and had been classified as azoospermic [50], oligozoospermic [50], asthenozoospermic [20] and normozoospermic [30] were studied for the analysis of serum LH, FSH, levels using Enzyme Immuno Assay [EIA]. Data were compared using student "t-test. The FSH and LH level indicated inverse/negative correlation to sperm concentration. The mean FSH and LH levels for the groups were 22.92 +/- 4.15 and 13.85 +/- 2.33 [Azoospermia], 16.82 +/- 3.79 and 10.92 +/- 3.79 [Oligozoospermia], 3.22 +/- 0.61 and 3.92 +/- 1.17 [Asthenozoospermia] while the levels in normozoospermic men were 5.53 +/- 0.52 and 7.40 +/- 0.60. Similarly, the LH/FSH and FSH/LH ratios in the four groups were 0.77 +/- 0.08 and 1.84 +/- 0.22 [Azoospermia], 1.78 +/- 0.41 and 1.47 +/- 0.18 [Oligozoospermia], 1.51 +/- 0.46 and 1.28 +/- 0.28 [Asthenozoospermia] and the respective ratios in normozoospermic men were 1.55 +/- 0.16 and 0.85 +/- 0.10. The present data indicate that disturbance in gonadotropin ratios also causes infertility, since these hormones act synergistically.

Comparative lipid profile studies in cardiac and diabetic conditions

Lipid profile in cardiac patients [myocardial infarction, angina pectoris, coronary heart disease, ischaemic heart disease], diabetic patients and normal humans was investigated. Total serum cholesterol, high density lipoprotein cholesterol [HDL-C], low density lipoprotein cholesterol [LDL-C], triglycerides, blood glucose, calcium, potassium and sodium were determined, employing established methods and procedures. Higher level of total cholesterol, LDL-C and triglyceride were found in both cardiac and diabetic patients, however, cardiac patients had much lower level of HDL-C as compared to normal humans. Age wise comparison revealed that level of total cholesterol; triglyceride and LDL-C were elevating while the level of HDL-C were decreasing with the age in cardiac and diabetic patients. Sex wise comparison showed that females had higher HDL-C level than males and therefore had fewer incidences of heart diseases. The level of Ca++, K+ and Na+ were similar in all age groups and sexes. No significant elevation in the level of these electrolytes was discovered